Seed & Series A in Denmark

Financing a Danish Biotech company has apparently never been more challenging.

Based on feedback from partnering meetings in 2025 it seems that raising Series A financing has become an unprecedented challenge. However, when looking at the available data on the frequency and size of Series A rounds, the situation appears less concerning (green bars)!?

To understand the disconnect between what companies are experiencing and what the data suggests, Sunstone has joined forces with the DANISH BIO – DANSK BIOTEK to try and quantify the missing piece of the puzzle: the actual need for Series A financing (in Denmark).

While data on completed Series A rounds is relatively accessible, it does not necessarily reflect the demand for such financings.

Most biotech companies receive Seed funding before raising a Series A. In Denmark, 90% of Series A rounds occur within four years of the initial Seed investment. We therefore estimated the current demand for Series A funding by summing all companies that received Seed financing, then subtracting those that have already raised a Series A and those that have passed the four-year mark without doing so. The remaining group represents the companies that are likely currently seeking Series A funding.

Since 2018, the number of companies receiving seed financing – and subsequently seeking Series A – has been rising, peaking in 2023. It has since started to decline, but the ageing seed portfolio (represented by dark blue in the figure) now reflects the growing difficulty of securing Series A financing in Denmark.

As of third quarter 2025, half of all seed-financed companies are more than two years into their seed round and could be “running on fumes”!

Is Denmark about to lose most of the companies that were created in 2018-2019 and received subsequent Seed Financed in the years that followed? Is the struggle to find Series A financing the cause of the declining number of new Danish biotech companies?

What do you think, are you seeing similar trends in your country? Feel free to let us know in the comments!

If you’re trying to raise a Series A and finding it tough—you’re not alone. Unfortunately!

What do you think?
Let us know in our feed on LinkedIn:

5 latest press releases

Treetop Meeting

We usually do not share updates from internal meetings - but this was too fantastic not to share. A full day meeting in the midst of branches of +100 year old oaks and beech trees overlooking Isefjorden in “the treetop huts” at Ryegaard & Trudsholm Godser. Spiced...

Hans T. Scambye joins Sunstone as Venture Partner

Sunstone is delighted to announce that experienced biotech executive and CEO of Galecto Hans T. Schambye will be joining our team as new Venture Partner as of 1st February 2025. With a background as an MD and PhD Hans brings to Sunstone over 25 years of experience...

Neumirna Therapeutics secures euro 20M in Series A financing

Neumirna Therapeutics (‘Neumirna’), an RNA-focused biotech company developing next-generation therapeutics for neurological disorders, is pleased to announce the first closing of its Series A funding round at €20M. The investment was co-led by new investors, Angelini...

Ascelia Pharma Successfully Meets Primary Endpoint with Strong Headline Results in Orviglance Phase 3 Study

Ascelia Pharma AB (publ) (ticker: ACE), a biotech focused on improving the life of people living with rare cancer conditions, today announced that liver imaging drug candidate, Orviglance®, significantly improved visualization of focal liver lesions, successfully...

Fund IV company Cardior Pharmaceuticals acquired by Novo Nordisk

Cardior is a leader in the discovery and development of therapies that target RNA as a means to prevent, repair and reverse diseases of the heart. The company’s therapeutic approach targets distinctive non-coding RNAs as a platform for addressing root causes of...

5 latest articles

Is biotech venture capital investing more to return less?

At Sunstone we continue to track risk-adjusted return multiples (adjusted for contingent payments) versus the total capital invested in private therapeutic companies prior to M&A exits. When looking at the median trends over the past 15 years, the inflection...

An update on M&A returns for biotech venture capital

Back in in 2019 Sunstone started sharing studies of European venture capital funded successes – i.e. M&A transactions. In 2021 we started adding US M&A’s to the data and later the same year we evaluated to which extent an IPO impacted the observations made....

Biotech ecosystem contributors!

Biotech ecosystem contributors! In our previous post, we discussed the importance of local investors and how, in a Danish context, they contribute to identifying and scaling local and regional therapeutic innovation. However, not all investors are born equal - and an...

Do local investors make a difference?

Do local investors make a difference? E-mail outreach, online meetings and digital data rooms have become a given when trying to finance a therapeutic innovation! So, do local or regional anchor investors matter when developing a bioinnovation ecosystem? If the local...

The 10 Advisements

We have the utmost respect for the courage, dedication, and resilience it takes to be an entrepreneur in our industry - especially when you’re out raising your next round of financing. That’s why we’ve decided to share our “10 Advisements” for crafting a compelling...

Saving Lives with Venture Capital

In 2023 we posted our thoughts on how to calculate the potential lifesaving impact of biotech venture capital (https://bit.ly/3z4mL0o) – and we promised to expand on the topic. Unfortunately, or rather fortunately, we got busy making investments in DioGenX, Kynexis...