Sunstone Capital today announce that the two investment arms of Sunstone – Life Science Ventures and Technology Ventures – in the future will operate under the names Sunstone Life Science Ventures ( https://sunstone.eu ) and Heartcore Capital, respectively.
Ascelia Pharma AB (“Ascelia Pharma” or the “Company”) has decided to issue new shares to the general public in Sweden and Denmark as well as institutional investors in Sweden and abroad (the “Offering”). The Company’s Board of Directors also intend to apply for admission to trading of the Company’s shares on Nasdaq Stockholm after Nasdaq Stockholm AB’s announcement that the Company complies with Nasdaq Stockholm’s listing requirements, provided that certain conditions and customary requirements, including the dispersion requirement for the Company’s shares, are fulfilled. The prospectus for the Offering, including the price and other terms of the Offering, is published today. The first day of trading is expected to be March 13, 2019.
Sunstone Life Science Ventures today announced the first closing of its Sunstone Life Science Ventures Fund IV (“Sunstone LSV IV”) at €80 million. The investment strategy of the new fund is a continuation of Sunstone’s successful strategy of investing in novel therapeutics with the potential to improve the quality of patient care and treatment. The typical investments are based on strong science and technology with innovative products addressing unmet medical needs within the framework of an attractive business case.
After a successful first closing of Sunstone Life Science Ventures Fund IV, Sunstone today announced the appointment of Jacob Lange Moresco, PhD, as Investment Director. Jacob will be joining Sunstone on 1 March 2019 and will be part of the team investing from the new fund.
Orphazyme A/S, a biopharmaceutical company dedicated to developing treatments for patients living with rare diseases, today announced the full data set for its Phase II/III clinical trial of arimoclomol in NPC, a devastating rare genetic disorder. Treatment with arimoclomol adjunct to routine clinical care resulted in a 74% reduction in disease progression (p-value =0.0506) as measured by the primary endpoint, 5-domain NPC Clinical Severity Scale (NPC-CSS). In the predefined subgroup of patients of 4 years and older (44 out of 50 randomized patients in the trial), the treatment difference was statistically significant with a minimal disease progression at month 12 in the arimoclomol-treated group (p-value =0.0219). A highly statistically significant treatment difference was observed in another predefined subgroup analysis, requested by the European Medicines Agency (EMA), that compared arimoclomol to placebo control in patients receiving miglustat as a part of routine clinical care (p-value =0.0071).