Santaris Pharma presents positive clinical data on SPC2996 in Chronic Lymphocytic Leukaemia.

Santaris Pharma, the Danish biopharmaceutical company, announced today that SPC2996, the Company’s new RNA Antagonist of Bcl-2, has shown early evidence of efficacy in an initial Phase I/II clinical study in Chronic Lymphocytic Leukaemia (CLL). The results of the study were reported this week at the 2007 Annual Meeting of the American Society of Clinical Oncology, held in Chicago, Illinois.

Santaris Pharma har udviklet den første nye lægemiddelkandidat i verden, som er rettet mod MicroRNA. Lægemiddelkandidaten skal nu videreudvikles af et MicroRNA Forskningskonsortium, som bliver støttet af Højteknologifonden med 10 mio. kr.

Det samlede budget for udviklingspro-jektet er 20 mio kr. MicroRNA Forskningskonsortiet består foruden Santaris Pharma af Center for Biologisk Sekvensanalyse (CBS), DTU samt Institut for Cellulær og Molekylær Medicin på Københavns Universitet MicroRNA, der forekommer naturligt i alle celler, er en nyopdaget klasse af små RNA molekyler, som regulerer aktiviteten af andre gener i cellen.

Ace Biosciences

Ace Biosciences in-licences phase I enterotoxigenic E Coli (ETEC) vaccine from Cambridge Biostability Ltd- Deal involves initial payment, milestone and royalties.

ACE BioSciences A/S, the infectious diseases company and Cambridge BioStability Ltd (CBL), the British biotechnology company have entered a strategic deal whereby ACE BioSciences in-licenses CBL’s ‘HolaVax’, (to be called ACE537) an oral Phase I Enterotoxigenic E Coli (ETEC) vaccine which has the potential to be the first to market in the US and EU and which combats the single biggest cause of travelers diarrhoea.

Santaris Pharma, the Danish biopharmaceutical company, announced today that Dr Flemming Ørnskov, Chief Executive Officer of Lifecycle Pharma A/S, has been elected non-executive Chairman of Santaris Pharma A/S.

Dr Ørnskov takes over responsibilities from Santaris Pharma’s current Chairman, Martien van Osch, a general partner at Forbion Capital Partners, with immediate effect. Dr Ørnskov was appointed to the Santaris Pharma Board by shareholders at the Company’s Annual General Meeting on 24th May 2007 and elected Chairman by the Santaris Pharma Board immediately thereafter.